Chromogranin A Antikörper
Kurzübersicht für Chromogranin A Antikörper (ABIN238334)
Target
Alle Chromogranin A (CHGA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein G
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Immunogen
- genetic immunisation with cDNA encoding CGA
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Isotyp
- IgG1
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Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
ELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, pH 7.2
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Chromogranin A (CHGA)
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Andere Bezeichnung
- Chromogranin A
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Hintergrund
- Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters. Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors.
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UniProt
- P10645
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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